Skypat P® Tablet

Aceclofenac & Paracetamol Tablets


Skypat P Tablets are a combination of  Aceclofenac (nonsteroidal anti-inflammatory agent – NSAIDs)and Paracetamol (an analgesic and antipyretic agent) that are used to treat pain and swelling. It is widely used in the treatment of Osteoarthritic pain, Rheumatoid Arthritis for pain management. It is commonly taken as an analgesic worldwide.

Key Benefits 

  • Significant symptomatic pain relief thereby improves the quality of life
  • Better GI tolerability than conventional NSAIDs
  • Offers synergistic analgesic action
  • Well tolerated and possesses a higher safety profile

Mode of action 

The mode of action of Aceclofenac is largely based on the inhibition of prostaglandin synthesis. Aceclofenac is a potent inhibitor of the enzyme cyclo-oxygenase COX-1 and COX-2), which is involved in the production of prostaglandins. Prostaglandins are the chemical substances released by the body and promote inflammation, pain (mild to moderate) and fever.

Paracetamol has analgesic (pain killer) and antipyretic (reduce fever) properties. It produces analgesia by blocking chemical messengers in the brain that causes pain and shows antipyretic activity by acting on the hypothalamus (a gland present in the brain and is responsible for regulating the body temperature).

Directions for use 

The recommended dosage is 1 Tablet to be taken twice daily after food or as directed by your physician 


  • Low Back pain
  • Post Operative pain
  • Osteoarthritic pain
  • Rheumatoid Arthritis
  • Spondylitis and Dental Pain

Side effects 

This medicine may cause side effects, although not everybody gets them. The most commonly observed adverse events are gastrointestinal in nature. Peptic ulcers, perforation or GI bleeding, sometimes fatal, particularly in the elderly, may occur. Nausea, vomiting, diarrhoea, flatulence, constipation, dyspepsia, abdominal pain, melaena, haematemesis, ulcerative stomatitis, exacerbation of colitis and Crohn’s disease. 

Storage and safety information 

  • Keep this medicine out of the sight and reach of children.
  • NSAIDs like Aceclofenac should not be used during pregnancy or labour unless the potential benefit to the patient outweighs the potential risk to the foetus.
  • In limited studies so far available, NSAIDs like Aceclofenac can appear in breast milk in very low concentrations.
  • SKYPAT-P should, if possible, be avoided when breastfeeding.